产品货号：
JN1944
中文名称：
重组错配尿嘧啶DNA糖基化酶(Mug)
英文名称：
Recombinant E. coli G/U Mismatch-Specific DNA Glycosylase/Mug
产品规格：
10μg|50μg|500μg|1mg
发货周期：
1～3天
产品价格：
询价
本品由我们的大肠杆菌表达系统制备而成，目标蛋白包含序列(Met1-Arg168) of E.coli Mug.
Mug质量控制：＞95%(SEC-HPLC，还原性SDS-PAGE)
Mug制剂：液体
Mug保存：
收到后请置于-20℃以下，可保存长达6个月，避免反复冻融。
关于Mug：
E. coli Mismatch Uracil DNA Glycosylase (Mug protein) is an 18 kDa constitutively expressed protein which belongs to the TDG/mug DNA glycosylase family. It has been proposed that the Mug protein excises 3,N4-ethenocytosine and removes the uracil base from mismatches in the order of U:G>U:A, although the biological role remains unclear. Uracil bases in DNA can arise from deamination of cytosine giving rise to increased spontaneous mutations. The enzyme Uracil-N-Glycosylase removes uracil from the DNA leaving an AP site. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. It is required for DNA damage lesion repair in stationary-phase cells.
相关搜索：重组错配尿嘧啶DNA糖基化酶(Mug)
Mug质量控制：＞95%(SEC-HPLC，还原性SDS-PAGE)
Mug制剂：液体
Mug保存：
收到后请置于-20℃以下，可保存长达6个月，避免反复冻融。
关于Mug：
E. coli Mismatch Uracil DNA Glycosylase (Mug protein) is an 18 kDa constitutively expressed protein which belongs to the TDG/mug DNA glycosylase family. It has been proposed that the Mug protein excises 3,N4-ethenocytosine and removes the uracil base from mismatches in the order of U:G>U:A, although the biological role remains unclear. Uracil bases in DNA can arise from deamination of cytosine giving rise to increased spontaneous mutations. The enzyme Uracil-N-Glycosylase removes uracil from the DNA leaving an AP site. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. It is required for DNA damage lesion repair in stationary-phase cells.
相关搜索：重组错配尿嘧啶DNA糖基化酶(Mug)